Chemical constituents of the extract from Dongge Ali
The chemical components isolated from different organs of Dongge Ali are mainly the diterpenoids of the quassinoid skeleton and canthin-6-one alkaloids, such as eurycomaoside, eurycolactone, eurycomalactone, eurycomanone and pasakbumin-B. In addition, it also contains biphenyl lignin, squalene derivatives, etc. 1. Terpenoids are mainly composed of diterpenoids with quassinoid skeleton, which are synthesized through triterpene degradation and found in roots and leaves. Bitter lignans compounds: lonilactone, 6-dehydrolonicactone, 11-dehydroclaineanone, 12-epi dehydroclaineanone, 15 β- hydroxyklaineanone、14，15 β- dihydroxyklaineanone、15- β- O-acetyl-14-hydroxyklaineanone, such compounds have anti-cancer and antiparasitic effects. There are four kinds of bitter wood gourmet in the root: pasakbumin-A, pasakbumin-B, pasakbumin-C and pasakbumin-D, of which pasakbumin-A (eurycomanone) and pasakbumin-B have the effect of anti ulcer. Gansuine type triterpenoids: 23, 24, 25 trihydroxyvirucalChemicalbookl-7-en-3, 6-dione, etc. 2. The alkaloids are mainly canthin-6-one alkaloids, which are found in roots, stems and branches. For example, scopolamine, 9, 10-dimethoxycannin-6-one, 10-hydroxy-9-methoxycannin-6-one, 11-hydroxy-10-methoxycannin-6-one, 5, 9-dimethoxycannin-6-one, 9-method-3-methylanthrin-5, 6-dione, 4, 9-dimethoxy-canthin-6-one and 10-hydroxy-11-methoxycannin-6-one, etc. 3. Volatile substances: curcumene, massoilactone, 3-Phenoxy-1-propanol, octanoicacid, benzoic, aceticacids, menthol, 2-Phenoxyethanol, 4-Ethynyl-4-hydroxy-3, 5, 5-trimethyl-2-cyclohex-1-enone. 4. Other scopoletin, 9-methodycanthin-6-one, 7-methody- β- Carbolin-1-proprionicacid, iandonol, etc.
