Pharmacological activity of the extract from Ali of Dongge
1. The anti-cancer activity was first reported in 1990. It was found that the longilactone, 13,21-dihydroeurycomanone, 14,15-dihydroxyklaineanone purified from Aligen Dongge had cytotoxicity to KB and P-388 cancer cell lines. The crude extract of Dongge Ali can induce apoptosis through the action of apoptosis protease, thereby inhibiting the growth of MCF-5 tumor cells. In addition, some scholars reported that the extract of Allium tonkinensis rich in enrycomenone can induce HepG2 cells apoptosis through P53 pathway. 2. The study on antimalarial activity found that the chloroform part and n-butanol part of the crude methanol extract of Aligenia tonkinensis had antimalarial activity. Quassinoids like compounds in the extract of Arilia tonkinensis can inhibit the synthesis of proteins in the body of malaria parasites into chemobooks, thus achieving the effect of anti malaria. 3. Improvement of sexual function After feeding the crude extract of Aligen dongge to the adult male rats with sexual experience, all the indicators of sexual function of the male rats were improved, while the adult male rats without sexual experience had sexual desire after feeding the crude extract, indicating that it had the effect of inducing sexual desire and improving sexual desire. After the estrogen treated rats were given the extract of Dongge Ali by gavage for 14 days, it was found that it could also promote the spermatogenesis of rats and increase the level of serum testosterone. Donggeli can enhance the vitality of the body, prolong the survival time of kidney deficiency mice under low temperature, increase the seminal vesicle and prostate index, and has a clear nourishing effect. 4. Other functions such as reducing blood sugar, antibacterial, treating gout, osteoporosis, improving energy and reducing fatigue; Improve physical and mental status; Promote appetite; Improve night free function; Anti hypertension; Anti ulcer and anti-virus; Antipyretic; Anti over teaching reaction; Improve the function of endocrine system.
